SCHEMBL28610643

SCHEMBL28610643

c1ccc(-c2nc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)nc(-c3ccc4ncccc4c3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.46
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
ABCB1 P08183 1/20 0.41
ABCC1 P33527 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
DYRK1A Q13627 1/20 0.39
MCL1 Q07820 1/20 0.38
ATR Q13535 1/20 0.38
AR P10275 1/20 0.37
CYP2A6 P11509 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
HPGD P15428 1/20 0.36
PIK3CD O00329 1/20 0.36
PIK3R1 P27986 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31379859 1.00 NPC1 (0.46) NPC1POLBRAB9AABCB1ABCC1
SCHEMBL22135430 0.95 NPC1 (0.48) NPC1POLBRAB9AABCB1ABCC1
SCHEMBL24328640 0.87 TDP2 (0.37) NPC1RAB9ACYP2A6AKR1C3AKR1C2
SCHEMBL12133795 0.86 MEN1 (0.46) POLBHPGDKDM4EMAPTSMN1; SMN2
SCHEMBL12133811 0.86 MEN1 (0.46) POLBHPGDKDM4EMAPTSMN1; SMN2
SCHEMBL17932666 0.85 MEN1 (0.41) HPGDKDM4EMAPTSMN1; SMN2MEN1
SCHEMBL22059105 0.85 TOP1 (0.39) ATRKDM4EMAPTSMN1; SMN2MEN1
SCHEMBL16772392 0.85 MEN1 (0.45) POLBHPGDKDM4EMAPTSMN1; SMN2
SCHEMBL17932736 0.85 MEN1 (0.45) POLBHPGDKDM4EMAPTSMN1; SMN2
SCHEMBL18468628 0.85 MEN1 (0.45) POLBHPGDKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195468-A Compound, and organic semiconductor layer, organic electronic device and display device comprising the same 诺瓦尔德股份有限公司 2021-07-30 CN disclosed