Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20423241 | 1.00 | — | — | |
| Oxalic Acid SCHEMBL30364755 | 0.89 | FFAR3 (0.40) | FFAR3LCKFYNLMNAALDH1A1 | |
| SCHEMBL725966 | 0.83 | — | — | |
| SCHEMBL727851 | 0.83 | — | — | |
| SCHEMBL6763327 | 0.83 | — | — | |
| Bicarbonate SCHEMBL21643681 | 0.81 | — | — | |
| Bicarbonate SCHEMBL10179891 | 0.81 | — | — | |
| Bicarbonate SCHEMBL1055054 | 0.80 | — | — | |
| SCHEMBL28156640 | 0.79 | — | — | |
| Bicarbonate SCHEMBL1058643 | 0.75 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108376799-B | Nonaqueous electrolyte solution and method for producing nonaqueous electrolyte secondary battery | 丰田自动车株式会社 | 2021-08-06 | — | — | CN | disclosed |