Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.79 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | CCR5 | P51681 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597480 | 0.96 | OPRM1 (0.82) | OPRM1ACHECCR5 | |
| SCHEMBL28599566 | 0.94 | OPRM1 (0.80) | OPRM1ACHECCR5 | |
| SCHEMBL28606816 | 0.94 | OPRM1 (0.74) | OPRM1ACHECCR5 | |
| SCHEMBL28602965 | 0.93 | OPRM1 (0.82) | OPRM1ACHE | |
| SCHEMBL28599565 | 0.85 | OPRM1 (1.00) | OPRM1 | |
| SCHEMBL28598353 | 0.85 | OPRM1 (1.00) | OPRM1 | |
| SCHEMBL28594954 | 0.85 | OPRM1 (0.78) | OPRM1ACHECCR5 | |
| SCHEMBL28604385 | 0.84 | OPRM1 (0.82) | OPRM1ACHECCR5 | |
| SCHEMBL28597473 | 0.83 | OPRM1 (0.92) | OPRM1 | |
| SCHEMBL28602605 | 0.83 | OPRM1 (1.00) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |