Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536318 | 0.89 | TUBB1 (0.51) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL4706617 | 0.86 | NPC1 (0.59) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL31500322 | 0.81 | MAPT (0.50) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL3629871 | 0.80 | NPC1 (0.59) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL1119262 | 0.80 | PRKDC (0.50) | TUBB1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL18397169 | 0.78 | ALDH1A1 (0.54) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL7147744 | 0.78 | TUBB1 (0.66) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL2196341 | 0.78 | NPC1 (0.61) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL28611584 | 0.78 | TUBB1 (0.74) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL13006159 | 0.78 | NPC1 (0.53) | TUBB1NPC1RAB9ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |