Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334801 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL5698514 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL5933911 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL4019607 | 0.77 | CYP2C19 (0.33) | TSHRCYP2C19 | |
| SCHEMBL28787467 | 0.77 | SMN1; SMN2 (0.35) | TSHRCYP2C19 | |
| SCHEMBL4360209 | 0.75 | CYP2C19 (0.34) | TSHRCYP2C19 | |
| SCHEMBL4169216 | 0.74 | CYP19A1 (0.41) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL4159330 | 0.74 | CYP19A1 (0.41) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL3679550 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL4225849 | 0.73 | SMN1; SMN2 (0.33) | TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705581-B | Silicone rubber composition, silicone rubber and preparation method thereof | 浙江清华柔性电子技术研究院 | 2021-07-13 | — | — | CN | disclosed |