SCHEMBL3679550

SCHEMBL3679550

C=CC(=O)OC1(O)CCC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.32
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933911 0.95 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9334801 0.93 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5698514 0.93 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL14642989 0.91
SCHEMBL16192556 0.80 EP300 (0.32) HIF1A
SCHEMBL673387 0.76 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28611779 0.74 KEAP1 (0.31) TSHR
SCHEMBL7912501 0.74 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7912504 0.74 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8530855 0.73 ALDH1A1 (0.37) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5854356-A Polymers for release films on surfaces containing pressure-sensitive adhesives NESTE OY (FI) 1998-12-29 US claimed
US-20100140833-A1 METHOD OF MANUFACTURING POLYOLEFIN-POLYAMIDE RESIN COMPOSITION UBE INDUSTRIES, LTD (JP) 2010-06-10 US disclosed
US-20080300342-A1 Polyolefin Resin Composition and Electric Wire Using the Same YAZAKI CORPORATION 2008-12-04 US disclosed
US-20070055040-A1 Method for the continuous synthesis of a liquid melamine resin AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2007-03-08 US disclosed
EP-1739125-A1 POLYOLEFIN RESIN COMPOSITION AND ELECTRIC WIRES MADE BY USING THE SAME YAZAKI CORPORATION (JP) 2007-01-03 EP disclosed
US-20060252909-A1 Direct synthesis method for the production of etherified melamine resin condensates, melemine resin condensates, and use thereof AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2006-11-09 US disclosed
US-20060231972-A1 Method for producing polyolefin-polyamide resin composition UBE INDUSTRIES, LTD. (JP) 2006-10-19 US disclosed
EP-1704977-A1 METHOD FOR PRODUCING POLYOLEFIN-POLYAMIDE RESIN COMPOSITION Ube Industries, Ltd. (JP) 2006-09-27 EP disclosed
US-20050250896-A1 Compositions for producing aminoplast products and method for producing products from these compositions AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2005-11-10 US disclosed
EP-0904958-B1 Pneumatic radial tire YOKOHAMA RUBBER CO LTD (JP) 2004-03-31 EP disclosed
US-6209603-B1 Pneumatic radial tire reinforced with fibrillated sea-island short polymer fibers THE YOKOHAMA RUBBER CO., LTD. (JP) 2001-04-03 US disclosed
EP-0760385-B1 Fine fiber-reinforced thermoplastic elastomer composition and process for producing same UBE INDUSTRIES (JP) 1999-11-17 EP disclosed
US-5948503-A Fine fiber reinforced thermoplastic elastomer composition and process for producing same UBE INDUSTRIES, LTD. (JP) 1999-09-07 US disclosed
EP-0904958-A2 Pneumatic radial tire THE YOKOHAMA RUBBER CO., LTD. (JP) 1999-03-31 EP disclosed
EP-0565734-B1 RESIN COMPOSITION AND MOLDING PRODUCED THEREFROM SHOWA DENKO KK (JP) 1999-01-27 EP disclosed
EP-0760385-A1 Fine fiber-reinforced thermoplastic elastomer composition and process for producing same UBE INDUSTRIES, LTD. (JP) 1997-03-05 EP disclosed
US-5395895-A Ethylene-maleic anhydride copolymer with polyhydric alcohol and catalysts SHOWA DENKO K.K. (JP) 1995-03-07 US disclosed
EP-0565734-A1 RESIN COMPOSITION AND MOLDING PRODUCED THEREFROM SHOWA DENKO KABUSHIKI KAISHA (JP) 1993-10-20 EP disclosed
EP-0092446-B1 THERMALLY CURABLE OLEFINIC POLYMERS AND MANUFACTURING METHOD FOR CURED SHAPED OBJECTS MADE THEREOF ELF ATOCHEM S.A. (FR) 1987-12-16 EP disclosed
EP-0092446-A1 Thermally curable olefinic polymers and manufacturing method for cured shaped objects made thereof ELF ATOCHEM S.A. (FR) 1983-10-26 EP disclosed