Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002678 | 0.84 | KCNH2 (0.43) | KCNH2CHRM4CHRM1KDM1AGPR119 | |
| SCHEMBL7569116 | 0.79 | KDM1A (0.47) | KCNH2CHRM4CHRM1KDM1AGPR119 | |
| SCHEMBL23570520 | 0.79 | POLB (0.43) | KCNH2CHRM4KDM1AGPR119POLB | |
| SCHEMBL20631821 | 0.73 | POLB (0.38) | KCNH2KDM1AGPR119POLB | |
| SCHEMBL23570688 | 0.73 | POLB (0.38) | KCNH2CHRM4KDM1AGPR119POLB | |
| SCHEMBL20631860 | 0.72 | KDM1A (0.39) | KCNH2CHRM4KDM1AGPR119POLB | |
| SCHEMBL20632140 | 0.72 | JAK1 (0.39) | KDM1AGPR119POLB | |
| SCHEMBL30968406 | 0.71 | KDM1A (0.39) | KCNH2CHRM4CHRM1KDM1AGPR119 | |
| SCHEMBL20630932 | 0.71 | POLB (0.36) | KCNH2CHRM4KDM1AGPR119POLB | |
| SCHEMBL31505870 | 0.70 | SLC18A3 (0.44) | KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113015526-A | Spirocyclic 2, 3-dihydro-7-azaindole compounds and uses thereof | 豪夫迈·罗氏有限公司 | 2021-06-22 | — | — | CN | disclosed |