Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611990 | 0.84 | KCNH2 (0.46) | KCNH2KDM1ACHRM4CHRM1POLB | |
| SCHEMBL7569116 | 0.81 | KDM1A (0.47) | KCNH2KDM1ACHRM4CHRM1POLB | |
| SCHEMBL1222469 | 0.81 | NOTUM (0.53) | KDM1AHDAC1HDAC8HDAC6P2RY1 | |
| SCHEMBL30413026 | 0.81 | NOTUM (0.53) | KDM1AHDAC1HDAC8HDAC6P2RY1 | |
| SCHEMBL23570520 | 0.81 | POLB (0.43) | KCNH2KDM1ACHRM4POLBP2RY1 | |
| SCHEMBL29640159 | 0.81 | KCNH2 (0.52) | KCNH2CHRM4CHRM1NOTUM | |
| Hydrochloric Acid SCHEMBL25232027 | 0.80 | NOTUM (0.52) | KDM1AHDAC1HDAC8HDAC6P2RY1 | |
| SCHEMBL6002974 | 0.77 | CYP11B2 (0.38) | KDM1AHDAC1HDAC8HDAC6P2RY1 | |
| SCHEMBL23570688 | 0.75 | POLB (0.38) | KCNH2KDM1ACHRM4POLBP2RY1 | |
| SCHEMBL20631821 | 0.75 | POLB (0.38) | KCNH2KDM1APOLBP2RY1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |