Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078337 | 0.96 | HDAC6 (0.64) | HDAC6HDAC1PTGDR2CYP2C9DDB1 | |
| SCHEMBL8097901 | 0.96 | HDAC6 (0.64) | HDAC6HDAC1PTGDR2CYP2C9DDB1 | |
| SCHEMBL28602909 | 0.91 | HDAC6 (0.59) | HDAC6HDAC1PTGDR2CYP2C9DDB1 | |
| SCHEMBL31078517 | 0.85 | HDAC6 (0.68) | HDAC6HDAC1PTGDR2CYP2C9KRAS | |
| SCHEMBL28618150 | 0.84 | PTGDR2 (0.62) | HDAC6HDAC1PTGDR2CYP2C9HDAC10 | |
| SCHEMBL2086484 | 0.83 | PTGDR2 (0.72) | HDAC6HDAC1PTGDR2CYP2C9PTGER2 | |
| SCHEMBL31078408 | 0.82 | HDAC6 (0.67) | HDAC6HDAC1PTGDR2CYP2C9KRAS | |
| SCHEMBL2248432 | 0.82 | HDAC6 (0.66) | HDAC6HDAC1PTGDR2CYP2C9KRAS | |
| SCHEMBL8105061 | 0.82 | HDAC6 (0.66) | HDAC6HDAC1PTGDR2CYP2C9KRAS | |
| SCHEMBL3306186 | 0.80 | CNR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |