Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243442 | 0.95 | PTGDR2 (0.59) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28605196 | 0.90 | PTGDR2 (0.54) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28605407 | 0.86 | PTGDR2 (0.52) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28612230 | 0.84 | HDAC6 (0.61) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL19132555 | 0.82 | PTGDR2 (0.66) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28617748 | 0.81 | HDAC6 (0.59) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL8097901 | 0.79 | HDAC6 (0.64) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL31078337 | 0.79 | HDAC6 (0.64) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL28607599 | 0.79 | PTGDR2 (0.62) | PTGDR2CYP2C9PTGER2PTGDRHDAC6 | |
| SCHEMBL3086512 | 0.78 | PTGDR2 (0.70) | PTGDR2CYP2C9PTGER2PTGDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |