Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613678 | 1.00 | MAPT (0.40) | MAPTPOLBTDP1CTDSP1ALDH1A1 | |
| SCHEMBL18952428 | 1.00 | MAPT (0.40) | MAPTPOLBTDP1CTDSP1ALDH1A1 | |
| SCHEMBL27336702 | 0.98 | MAPT (0.39) | MAPTPOLBTDP1CTDSP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27340797 | 0.98 | MAPT (0.39) | MAPTPOLBTDP1CTDSP1ALDH1A1 | |
| SCHEMBL1783386 | 0.83 | MAPT (0.56) | MAPTPOLBTDP1CTDSP1 | |
| SCHEMBL18952446 | 0.79 | MAPT (0.35) | MAPT | |
| SCHEMBL14540357 | 0.78 | MAPT (0.40) | MAPT | |
| SCHEMBL27337938 | 0.78 | MAPT (0.47) | MAPT | |
| SCHEMBL26451960 | 0.78 | MAPT (0.47) | MAPT | |
| SCHEMBL10787960 | 0.77 | MAPT (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430963-B | Compound (I) | 奇华顿股份有限公司 | 2021-08-20 | — | — | CN | disclosed |