SCHEMBL1783386

SCHEMBL1783386

CC(=O)C1CCC=CC1C

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.56
POLB P06746 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28613678 0.83 MAPT (0.40) MAPTPOLBCTDSP1TDP1
SCHEMBL28612387 0.83 MAPT (0.40) MAPTPOLBCTDSP1TDP1
SCHEMBL18952428 0.83 MAPT (0.40) MAPTPOLBCTDSP1TDP1
SCHEMBL10787960 0.82 MAPT (0.38) MAPT
SCHEMBL27336702 0.81 MAPT (0.39) MAPTPOLBCTDSP1TDP1
Ammonia Solution, Strong SCHEMBL27340797 0.81 MAPT (0.39) MAPTPOLBCTDSP1TDP1
SCHEMBL28613787 0.79 MAPT (0.38) MAPT
SCHEMBL18952544 0.79 MAPT (0.38) MAPT
SCHEMBL17085339 0.78 MAPT (0.51) MAPT
SCHEMBL18165565 0.78 MAPT (0.51) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
WO-2005012222-A1 ALICYCLIC ESTER WITH MUSK FRAGRANCE SYMRISE GMBH & CO. KG (DE) 2005-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 MAPT 906/4885POLB 1955/4885CTDSP1 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.