Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603867 | 0.87 | TP53 (0.39) | EPHX2BTKKDM1AMAOBCTSK | |
| SCHEMBL27415413 | 0.85 | EPHX2 (0.36) | EPHX2BTKKDM1AMAOBCTSK | |
| SCHEMBL27415382 | 0.84 | ABL1 (0.34) | ABL1NPC1RAB9A | |
| SCHEMBL31563954 | 0.78 | EPHX2 (0.43) | EPHX2BTKKDM1AMAOBCTSK | |
| SCHEMBL31564173 | 0.77 | EPHX2 (0.43) | EPHX2BTKKDM1AMAOBCTSK | |
| SCHEMBL28607624 | 0.76 | ALDH1A1 (0.38) | BTKKMT2ARAB9A | |
| Trifluoroacetic Acid SCHEMBL28611854 | 0.74 | ABL1 (0.36) | ABL1 | |
| SCHEMBL28615820 | 0.72 | MAPT (0.49) | KMT2A | |
| SCHEMBL28613536 | 0.72 | MAPT (0.49) | KMT2A | |
| SCHEMBL29371263 | 0.72 | NPC1 (0.47) | EPHX2DRD2KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |