Sugi Predict

Sugi Predict / Compounds / SCHEMBL2861286

SCHEMBL2861286

SCHEMBL2861286

Cc1ccc(-c2nc3cccc(Nc4ccc([N+](=O)[O-])cc4)c3nc2-c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 0.50
▸ POLB P06746 2/20 0.50
▸ MAPT P10636 6/20 0.49
▸ HTT P42858 3/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ JAK2 O60674 1/20 0.49
▸ MITF O75030 1/20 0.49
▸ PAX8 Q06710 1/20 0.49
▸ MEN1 O00255 6/20 0.45
▸ MAPK1 P28482 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ IDO1 P14902 1/20 0.44
▸ ALDH1A1 P00352 5/20 0.43
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2855051 0.89 KMT2A (0.58) KMT2APOLBMAPTHTTMEN1
SCHEMBL2855203 0.88 TYMS (0.52) KMT2APOLBMAPTSMN1; SMN2MEN1
SCHEMBL2857740 0.82 TDP1 (0.45) KMT2APOLBMAPTSMN1; SMN2MEN1
SCHEMBL13172280 0.81 TP53 (0.42) KMT2APOLBMAPTHTTMEN1
SCHEMBL2861009 0.78 ABCG2 (0.54) KMT2APOLBMAPTHTTSMN1; SMN2
SCHEMBL2862878 0.76 MEN1 (0.76) KMT2APOLBMAPTHTTSMN1; SMN2
SCHEMBL2866108 0.76 KMT2A (0.58) KMT2APOLBMAPTHTTSMN1; SMN2
SCHEMBL2867194 0.73 MAPT (0.47) KMT2APOLBMAPTHTTSMN1; SMN2
SCHEMBL4626757 0.72 HSD17B10 (0.75) KMT2AMAPTHTTSMN1; SMN2JAK2
SCHEMBL2868196 0.70 KDM1A (0.48) KMT2AMAPTHTTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1713101-B1 ELECTRODE FOR ENERGY STORAGE DEVICE AND PROCESS FOR PRODUCING THE SAME UNIV YAMAGUCHI (JP) 2012-10-31 — — EP disclosed
US-7803898-B2 Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-28 — — US disclosed
US-7803898-B2 Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-28 — — US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 — — US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 — — US disclosed
US-7799894-B2 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2010-09-21 — — US disclosed
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 — — US disclosed
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 — — US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 — — US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 — — US disclosed
US-20070120112-A1 copolymer of diaminobenzene with a diamine containing substituted quinoxaline ring (2,3-diphenyl-5-(4-aminophenyl)aminoquinoxaline, 2,3-di(4-methylphenyl)-5-(4-aminophenyl)aminoquinoxaline; Poly{2,3-di(2-thienyl)-5-(4-aminophenyl)aminoquinoxaline; polyaminequinoxalines YAMAGUCHI UNIVERSITY (JP) 2007-05-31 — — US disclosed
EP-1713101-A1 ELECTRODE FOR ENERGY STORAGE DEVICE AND PROCESS FOR PRODUCING THE SAME Yamaguchi University (JP) 2006-10-18 — — EP disclosed
EP-1705178-A1 AMINOQUINOXALINE COMPOUND, POLYAMINOQUINOXALINE COMPOUND, AND USE THEREOF Nissan Chemical Industries, Ltd. (JP) 2006-09-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030176-A1 Aminoquinoxaline Compound, Polyaminoquinoxaline Compound, and Use Thereof PAM, CYC1, QPCT KMT2A 513/4885POLB 1551/4885MAPT 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.