SCHEMBL28612865

SCHEMBL28612865

Pc1ccccc1.Pc1ccccc1.[Pd]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
TSHR P16473 5/20 0.35
TDP1 Q9NUW8 5/20 0.35
CA1 P00915 3/20 0.35
CA9 Q16790 3/20 0.35
ALOX12 P18054 3/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.35
CA7 P43166 1/20 0.35
HSD17B10 Q99714 3/20 0.33
CYP2A6 P11509 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601130 1.00
SCHEMBL1852390 1.00
SCHEMBL29457685 1.00 ALDH1A1 (0.40) ALDH1A1TSHRTDP1CA1CA9
SCHEMBL774871 1.00 ALDH1A1 (0.40) ALDH1A1TSHRTDP1CA1CA9
Hydrochloric Acid SCHEMBL22471233 0.96 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA1CA9
Hydrochloric Acid SCHEMBL8521950 0.96
Benzene SCHEMBL28128746 0.96 ALDH1A1 (0.43) ALDH1A1TSHRTDP1CA1CA9
SCHEMBL49436 0.96
Bromide SCHEMBL10514507 0.92 ALDH1A1 (0.40) ALDH1A1TSHRTDP1CA1CA9
Water SCHEMBL22231695 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109061-A Tricyclic compounds 北京加科思新药研发有限公司 2022-09-27 CN disclosed
CN-112513041-B Tricyclic compounds 北京加科思新药研发有限公司 2022-05-10 CN disclosed
CN-112513041-A Tricyclic compounds 北京加科思新药研发有限公司 2021-03-16 CN disclosed