Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 6/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16470235 | 1.00 | CACNA1B (0.51) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL23029169 | 0.93 | CACNA1B (0.45) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL16469897 | 0.88 | CACNA1B (0.52) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL28628007 | 0.88 | CACNA1B (0.52) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL16330581 | 0.88 | CACNA1B (0.52) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL18460015 | 0.86 | HDAC4 (0.51) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL30445735 | 0.85 | CACNA1B (0.55) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL5351823 | 0.85 | CACNA1B (0.67) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL2064232 | 0.84 | CACNA1B (0.51) | CACNA1BCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL2063543 | 0.84 | CACNA1B (0.51) | CACNA1BCTSKCTSSHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053723-B | Sulfonamide derivatives and pharmaceutical use thereof | EA制药株式会社 | 2021-09-03 | — | — | CN | disclosed |