SCHEMBL28613209 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	10/20	0.35

▸	ALDH1A1	P00352	2/20	0.33

▸	TSHR	P16473	1/20	0.32

▸	KDM5A	P29375	1/20	0.32

▸	TP53	P04637	1/20	0.31

▸	F10	P00742	1/20	0.31

▸	ST14	Q9Y5Y6	1/20	0.31

▸	TPSAB1	Q15661	1/20	0.30

▸	EPHX1	P07099	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28613211	1.00	EPHX2 (0.35)	EPHX2ALDH1A1TSHRKDM5ATP53
SCHEMBL28625098	0.87	EPHX2 (0.44)	EPHX2EPHX1
SCHEMBL20873024	0.72	DPP7 (0.41)	EPHX2KDM5AEPHX1
SCHEMBL28613203	0.70	EPHX2 (0.44)	EPHX2KDM5AEPHX1
SCHEMBL28613201	0.70	EPHX2 (0.44)	EPHX2KDM5AEPHX1
Methyl Carbamate SCHEMBL28611639	0.70	METAP1 (0.43)	EPHX2KDM5A
SCHEMBL28624308	0.70	EPHX2 (0.48)	EPHX2EPHX1
SCHEMBL28624310	0.70	EPHX2 (0.48)	EPHX2EPHX1
SCHEMBL20881530	0.68	EPHX2 (0.39)	EPHX2KDM5AF10ST14EPHX1
SCHEMBL28611637	0.68	DPP7 (0.41)	EPHX2KDM5AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-107098871-B	Phenyl propionamide derivative, preparation method and medical application thereof	江苏恒瑞医药股份有限公司	2021-07-02	—	—	CN	disclosed