Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613203 | 1.00 | EPHX2 (0.44) | EPHX2DPP7ARG1TLR9TLR8 | |
| SCHEMBL28624308 | 0.93 | EPHX2 (0.48) | EPHX2DPP7ITGB3ITGA2BEPHX1 | |
| SCHEMBL28624310 | 0.93 | EPHX2 (0.48) | EPHX2DPP7ITGB3ITGA2BEPHX1 | |
| SCHEMBL19708437 | 0.85 | EPHX1 (0.46) | EPHX2DPP7ITGB3ITGA2BDPP8 | |
| SCHEMBL28581494 | 0.85 | EPHX1 (0.46) | EPHX2DPP7ITGB3ITGA2BDPP8 | |
| SCHEMBL21009781 | 0.84 | EPHX1 (0.46) | EPHX2DPP7ITGB3ITGA2BDPP8 | |
| SCHEMBL20873024 | 0.83 | DPP7 (0.41) | EPHX2DPP7DPP8DPP9EPHX1 | |
| Methyl Carbamate SCHEMBL28611639 | 0.81 | METAP1 (0.43) | EPHX2DPP7DPP8DPP9KDM5A | |
| SCHEMBL28624318 | 0.81 | ALDH1A1 (0.39) | EPHX2 | |
| SCHEMBL28628330 | 0.81 | DPP7 (0.41) | EPHX2DPP7DPP8DPP9EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |