Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664028 | 1.00 | LMNA (0.46) | LMNATHRBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3152062 | 0.92 | PRKDC (0.42) | LMNATHRBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28618361 | 0.82 | PRKDC (0.36) | LMNAALDH1A1CYP1A2CYP2C19PRKDC | |
| SCHEMBL8198276 | 0.80 | ERN1 (0.46) | LMNATHRBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28608013 | 0.79 | PRKDC (0.41) | LMNAALDH1A1CYP1A2CYP2C19PRKDC | |
| SCHEMBL28610814 | 0.79 | ERN1 (0.50) | LMNAPRKDCERN1MAPT | |
| SCHEMBL28624223 | 0.79 | PRKDC (0.41) | LMNAALDH1A1CYP1A2CYP2C19PRKDC | |
| SCHEMBL19381723 | 0.78 | ERN1 (0.44) | LMNAALDH1A1CYP1A2CYP2C19PRKDC | |
| SCHEMBL7815397 | 0.78 | LMNA (0.54) | LMNATHRBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27261303 | 0.76 | PRKDC (0.43) | LMNAALDH1A1PRKDCERN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |