Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613489 | 1.00 | LMNA (0.36) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9194202 | 0.80 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28979601 | 0.79 | LMNA (0.34) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29728550 | 0.75 | LMNA (0.48) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27842797 | 0.75 | — | — | |
| SCHEMBL20504237 | 0.75 | — | — | |
| SCHEMBL8755732 | 0.74 | — | — | |
| SCHEMBL18043494 | 0.74 | — | — | |
| SCHEMBL28607903 | 0.74 | LMNA (0.33) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL745345 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661084-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2021-08-31 | — | — | CN | disclosed |