⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704139 | 0.88 | — | — | |
| SCHEMBL1227396 | 0.80 | — | — | |
| SCHEMBL11673918 | 0.79 | TSHR (0.46) | — | |
| SCHEMBL6734294 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL11759856 | 0.73 | — | — | |
| SCHEMBL10960367 | 0.73 | — | — | |
| SCHEMBL9420696 | 0.71 | — | — | |
| SCHEMBL10489497 | 0.71 | — | — | |
| SCHEMBL11271214 | 0.71 | — | — | |
| SCHEMBL3792845 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227131-A | Modified antibody Fc and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-112955124-A | Oral film compositions and dosage forms having precise active dissolution profiles | 阿奎蒂夫疗法公司 | 2021-06-11 | — | — | CN | disclosed |