Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304452 | 1.00 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5449980 | 1.00 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11411120 | 0.86 | SIRT2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11411127 | 0.86 | SIRT2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13832484 | 0.84 | NFE2L2 (0.53) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11410251 | 0.83 | SIRT2 (0.43) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11403016 | 0.83 | NFE2L2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11403018 | 0.83 | NFE2L2 (0.46) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14337490 | 0.83 | SIRT2 (0.56) | SIRT2POLBMAOBCA1CA2 | |
| SCHEMBL11410253 | 0.83 | SIRT2 (0.43) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045454-B | Catalytic synthesis method and application of nitrile compound | 吉林大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113045454-A | Catalytic synthesis method and application of nitrile compound | 吉林大学 | 2021-06-29 | — | — | CN | disclosed |