Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528335 | 0.83 | MEN1 (0.38) | GRIN1GRIN2BSIRT2ADORA3ADORA2B | |
| SCHEMBL26999043 | 0.76 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL23528322 | 0.75 | KMT2A (0.41) | MAPTAKR1B1MEN1KMT2A | |
| SCHEMBL26434012 | 0.67 | KMT2A (0.37) | NPC1HTTRAB9ASMN1; SMN2MAPT | |
| SCHEMBL23528559 | 0.66 | STAT3 (0.41) | GRIN1GRIN2BSIRT2NPC1HTT | |
| SCHEMBL23297351 | 0.64 | TP53 (0.48) | MEN1KMT2A | |
| SCHEMBL20435725 | 0.61 | HPGD (0.58) | SIRT2NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL20435870 | 0.61 | HPGD (0.58) | SIRT2NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28912728 | 0.61 | SIRT2 (0.71) | SIRT2S1PR1NPC1HTTRAB9A | |
| SCHEMBL20435887 | 0.61 | RAB9A (0.62) | SIRT2S1PR1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272291-A | Pyridazinone compound and use thereof | 艾知怀斯治疗学公司 | 2021-08-17 | — | — | CN | disclosed |