Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693379 | 0.93 | GAA (0.46) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL28613624 | 0.91 | GAA (0.44) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL11660322 | 0.79 | GAA (0.46) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL10766470 | 0.75 | GAA (0.53) | GAAKDM4EGLAPOLBHPGD | |
| Benzene SCHEMBL11102681 | 0.75 | GAA (0.52) | GAAKDM4EGLAPOLBHPGD | |
| SCHEMBL2897337 | 0.74 | GAA (0.41) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL29055850 | 0.74 | GAA (0.41) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL23174748 | 0.71 | MGAM (0.32) | GAAMGAMSIMGAM2 | |
| SCHEMBL17137897 | 0.71 | GAA (0.48) | GAAKDM4EGLAPOLBHSD17B10 | |
| SCHEMBL9751345 | 0.71 | GAA (0.42) | GAAKDM4EGLAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |