Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613624 | 0.98 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| Benzene SCHEMBL28614679 | 0.93 | GAA (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11660322 | 0.85 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29055850 | 0.79 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2897337 | 0.79 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL23174748 | 0.76 | MGAM (0.32) | GAAMGAMSIMGAM2 | |
| SCHEMBL17137897 | 0.76 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9751345 | 0.76 | GAA (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28538773 | 0.75 | ACHE (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL11879740 | 0.73 | MEN1 (0.39) | GAAALDH1A1LMNAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169144-B1 | PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES | GEMA S.A. (ES) | 1990-06-06 | — | — | EP | claimed |
| EP-0034394-B1 | PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1984-08-01 | — | — | EP | claimed |
| EP-0017170-B1 | IMPROVED PROCESS FOR THE PREPARATION OF CEPHAMYCIN ANTIBIOTICS | MERCK & CO. INC. (US) | 1983-04-13 | — | — | EP | claimed |
| US-4366315-A | Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds | GIST-BROCADES N.V. (NL) | 1982-12-28 | — | — | US | claimed |
| EP-0034394-A2 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1981-08-26 | — | — | EP | claimed |
| EP-0017170-A1 | Improved process for the preparation of cephamycin antibiotics | MERCK & CO. INC. (US) | 1980-10-15 | — | — | EP | claimed |
| US-4218563-A | TRANSACYLATION IN PRESENCE OF N-TRIMETHYLSILYL LOWER ALKYL CARBAMATES | MERCK & CO., INC. (US) | 1980-08-19 | — | — | US | claimed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | claimed |
| EP-4381070-A2 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | Phio Pharmaceuticals Corp. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116490180-B | Methods of treating CNS disorders | 杭州高光制药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-113166592-B | Cold formed glass article with dual binder system and process for cold forming glass article | 康宁公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-4308576-A1 | NEW THIAZOLOPYRIMIDINONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| EP-0034394-A2 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1981-08-26 | — | — | EP | disclosed |
| US-4284766-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4258183-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |
| US-4107432-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4058661-A | 7-Diacyl cephalosporins | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |