SCHEMBL28614701

SCHEMBL28614701

O=C(NCC#CI)OCCO

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.50
CHRNB2 P17787 2/20 0.37
CHRNB4 P30926 2/20 0.37
CHRNA3 P32297 2/20 0.37
CHRNA4 P43681 2/20 0.37
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677162 0.85 ACHE (0.46) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL28595382 0.83 ACHE (0.36) ACHECHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL337339 0.81 ACHE (0.53) ACHEALDH1A1
SCHEMBL6688659 0.80 ACHE (0.56) ACHE
SCHEMBL29132933 0.80 GAA (0.41) ACHETSHRALDH1A1
SCHEMBL677758 0.79 ACHE (0.59) ACHE
SCHEMBL29132868 0.77
SCHEMBL6683165 0.74 MAPT (0.39) TSHRALDH1A1
SCHEMBL25174640 0.73
SCHEMBL5249543 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113226026-A Encapsulated fungicides 隆萨解决方案股份公司 2021-08-06 CN disclosed