Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 15/20 | 0.43 |
| ▸ | JAK2 | O60674 | 13/20 | 0.43 |
| ▸ | JAK1 | P23458 | 12/20 | 0.43 |
| ▸ | TYK2 | P29597 | 8/20 | 0.43 |
| ▸ | STAT3 | P40763 | 4/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956503 | 0.89 | JAK1 (0.45) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL24852535 | 0.88 | JAK3 (0.47) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL24852537 | 0.82 | JAK3 (0.48) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL30956481 | 0.81 | JAK3 (0.49) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL27447231 | 0.79 | JAK3 (0.51) | JAK3JAK2JAK1TYK2 | |
| SCHEMBL28919422 | 0.78 | JAK2 (0.44) | JAK3JAK2JAK1TYK2 | |
| SCHEMBL22097913 | 0.77 | JAK3 (0.49) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL28919841 | 0.76 | JAK2 (0.40) | JAK3JAK2JAK1TYK2STAT3 | |
| SCHEMBL28606148 | 0.76 | IGF1R (0.44) | JAK3JAK2JAK1TYK2 | |
| SCHEMBL30956393 | 0.74 | JAK2 (0.53) | JAK3JAK2JAK1TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290403-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |