Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.67 |
| ▸ | JAK2 | O60674 | 7/20 | 0.67 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | JAK3 | P52333 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173293 | 1.00 | JAK1 (0.67) | JAK1JAK2NUDT1JAK3ATM | |
| SCHEMBL28603790 | 0.88 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL30173268 | 0.88 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL28598989 | 0.87 | JAK1 (0.71) | JAK1JAK2 | |
| SCHEMBL30173341 | 0.87 | JAK1 (0.71) | JAK1JAK2 | |
| SCHEMBL28594552 | 0.83 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL30173297 | 0.83 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL30173292 | 0.82 | JAK1 (0.64) | JAK1JAK2NUDT1JAK3 | |
| SCHEMBL22869250 | 0.81 | JAK1 (0.73) | JAK1JAK2JAK3 | |
| SCHEMBL30173344 | 0.81 | JAK1 (0.69) | JAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-113200983-A | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-03 | — | — | CN | disclosed |