Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 17/20 | 0.64 |
| ▸ | JAK2 | O60674 | 10/20 | 0.64 |
| ▸ | JAK3 | P52333 | 4/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597942 | 1.00 | JAK1 (0.64) | JAK1JAK2JAK3NUDT1ADORA1 | |
| SCHEMBL28594552 | 0.88 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL30173297 | 0.88 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL28603790 | 0.86 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL30173268 | 0.86 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL28602167 | 0.83 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL30173303 | 0.83 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL28919429 | 0.83 | JAK1 (0.62) | JAK1JAK2JAK3 | |
| SCHEMBL30173293 | 0.82 | JAK1 (0.67) | JAK1JAK2JAK3NUDT1 | |
| SCHEMBL28614739 | 0.82 | JAK1 (0.67) | JAK1JAK2JAK3NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |