SCHEMBL28614867

SCHEMBL28614867

CC(=O)n1cc(C(=O)Nc2ccc(C3CCCC3)cc2C(=O)O)c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 20/20 0.68
EP300 Q09472 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28620505 0.99 CREBBP (0.69) CREBBPEP300
SCHEMBL28616461 0.96 CREBBP (0.67) CREBBPEP300
SCHEMBL28623973 0.81 CREBBP (0.65) CREBBPEP300
SCHEMBL28617513 0.80 KDM4E (0.68) CREBBPEP300
SCHEMBL28616565 0.79 CREBBP (0.77) CREBBPEP300
SCHEMBL28614746 0.78 CREBBP (0.70) CREBBPEP300
SCHEMBL28612022 0.78 CREBBP (0.67) CREBBPEP300
SCHEMBL28620491 0.78 CREBBP (0.71) CREBBPEP300
SCHEMBL28613830 0.77 CREBBP (0.68) CREBBPEP300
SCHEMBL28613652 0.75 CREBBP (0.68) CREBBPEP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113321640-B Indole compound and application thereof 中国科学院广州生物医药与健康研究院 2023-06-09 CN disclosed
CN-109111427-B Indole compound and application thereof 中国科学院广州生物医药与健康研究院 2023-06-02 CN disclosed
CN-113321640-A Indole compound and application thereof 中国科学院广州生物医药与健康研究院 2021-08-31 CN disclosed