Phosphoric Acid

Phosphoric Acid

SCHEMBL2861492

O=P(O)(O)O.[H-].[K+]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021037127-A1 BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR 上海特化医药科技有限公司 2021-03-04 WO claimed
US-11246932-B2 Prostaglandin compositions and methods for the treatment of vasospasm NEXMED HOLDINGS, INC. (US) 2022-02-15 US disclosed
WO-2021037127-A1 BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR 上海特化医药科技有限公司 2021-03-04 WO disclosed
US-20190076529-A1 PROSTAGLANDIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF VASOSPASM NEXMED HOLDINGS, INC. (US) 2019-03-14 US disclosed
US-20150272875-A1 ALPROSTADIL FOR TREATMENT OF PREMATURE EJACULATION NEXMED HOLDINGS, INC. (US) 2015-10-01 US disclosed
US-9066854-B2 Alprostadil and dyclonine for treatment of premature ejaculation NEXMED HOLDINGS, INC. (US) 2015-06-30 US disclosed
US-9060929-B2 Alprostadil for treatment of premature ejaculation NEXMED HOLDINGS, INC. (US) 2015-06-23 US disclosed
US-9056044-B2 Alprostadil and lidocaine treatment of premature ejaculation NEXMED HOLDINGS, INC. (US) 2015-06-16 US disclosed
US-20150011585-A1 ALPROSTADIL AND DYCLONINE FOR TREATMENT OF PREMATURE EJACULATION NEXMED HOLDINGS, INC. (US) 2015-01-08 US disclosed
US-20150011638-A1 ALPROSTADIL AND LIDOCAINE TREATMENT OF PREMATURE EJACULATION NEXMED HOLDINGS, INC. (US) 2015-01-08 US disclosed
CN-1137086-C 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof ������ҩ��ʽ���� 2004-02-04 CN disclosed
US-20030220292-A1 Treatment of erectile dysfunction NEXMED (HOLDINGS), INC. 2003-11-27 US disclosed
WO-2003070281-A1 PROSTAGLANDIN COMPOSITION FOR THE TREATMENT OF ERECTILE DYSFUNCTION NEXMED (HOLDINGS), INC. (US) 2003-08-28 WO disclosed
US-20030134903-A1 Prostaglandin compositions and methods of treatment for male erectile dysfunction NEXMED (HOLDINGS), INC. 2003-07-17 US disclosed
WO-2003022310-A1 PROSTAGLANDIN COMPOSITIONS AND METHODS OF TREATMENT FOR MALE ERECTILE DYSFUNCTION NEXMED HOLDINGS, INC. (US) 2003-03-20 WO disclosed
EP-1255552-A1 PROSTAGLANDIN COMPOSITIONS AND METHODS OF TREATMENT FOR MALE ERECTILE DYSFUNCTION Nexmed Holdings, Inc. (US) 2002-11-13 EP disclosed
US-6414028-B1 MIXTURE WITH SKIN PENETRATION INTENSIFIER, POLYSACCHARIDE GUM AND BUFFER NEXMED HOLDINGS, INC. 2002-07-02 US disclosed
US-20020045665-A1 Prostaglandin compositions and methods of treatment for male erectile dysfunction NEXMED (HOLDINGS), INC. 2002-04-18 US disclosed
WO-2001051053-A1 PROSTAGLANDIN COMPOSITIONS AND METHODS OF TREATMENT FOR MALE ERECTILE DYSFUNCTION NEXMED HOLDINGS, INC. (US) 2001-07-19 WO disclosed
CN-1259117-A 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof YOSHITOMI PHARMACEUTICAL (JP) 2000-07-05 CN disclosed