Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | GPX4 | P36969 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617480 | 0.92 | KMT2A (0.73) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL28920591 | 0.90 | KMT2A (0.63) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL8252701 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1GPX4TRPV1 | |
| SCHEMBL997520 | 0.85 | KMT2A (0.78) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL998500 | 0.84 | KMT2A (0.84) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL28606538 | 0.82 | KMT2A (0.76) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL5787110 | 0.81 | HDAC1 (0.74) | HDAC6HDAC1 | |
| SCHEMBL998353 | 0.81 | KMT2A (0.71) | HDAC6HDAC1KMT2ADRD2DRD3 | |
| SCHEMBL1000934 | 0.80 | GPX4 (0.63) | KMT2AGPX4TRPV1 | |
| SCHEMBL999152 | 0.80 | KMT2A (0.72) | KMT2ADRD2DRD3GPX4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |