Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183911 | 0.76 | HPGD (0.50) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5048054 | 0.72 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1L3MBTL1ACACB | |
| SCHEMBL3644126 | 0.71 | GRM5 (0.71) | HPGDSMN1; SMN2ALDH1A1L3MBTL1ACACB | |
| SCHEMBL104961 | 0.71 | ALDH1A1 (0.71) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21360559 | 0.70 | HPGD (0.60) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3644132 | 0.70 | EPHX2 (0.66) | HPGDSMN1; SMN2ALDH1A1L3MBTL1ACACB | |
| SCHEMBL10720943 | 0.70 | PHGDH (0.81) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL23095843 | 0.69 | PHGDH (0.65) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7338701 | 0.69 | PHGDH (0.65) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL20183883 | 0.69 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349874-B | Compound having BLT inhibitory activity and composition for preventing or treating inflammatory disease comprising the same as active ingredient | 东国大学校产学协力团 | 2021-07-27 | — | — | CN | disclosed |