Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.62 |
| ▸ | RORC | P51449 | 3/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | CPT2 | P23786 | 3/20 | 0.43 |
| ▸ | CPT1A | P50416 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627883 | 0.88 | NR1H3 (0.59) | NR1H3RORCNR1H2CYP2C9CPT2 | |
| SCHEMBL28614471 | 0.83 | NR1H3 (0.61) | NR1H3RORCNR1H2MAPTCYP2C9 | |
| SCHEMBL2002839 | 0.81 | RORC (0.48) | NR1H3RORCNR1H2MAPTCYP2C9 | |
| SCHEMBL28626488 | 0.79 | POLB (0.49) | NR1H3RORCMAPTNPC1MEN1 | |
| SCHEMBL28617165 | 0.79 | SCN9A (0.51) | NR1H3MAPTNPC1MEN1KMT2A | |
| SCHEMBL28922176 | 0.79 | HDAC1 (0.46) | NPC1KMT2A | |
| SCHEMBL20270381 | 0.77 | MEN1 (0.44) | NR1H3RORCNR1H2CYP2C9CPT2 | |
| SCHEMBL23619075 | 0.77 | RORC (0.46) | NR1H3RORCNR1H2MAPTCYP2C9 | |
| SCHEMBL2001054 | 0.76 | CNR1 (0.57) | NR1H3RORCNR1H2MAPTMCL1 | |
| SCHEMBL28624617 | 0.75 | RORC (0.44) | RORCNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |