Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | INMT | O95050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824179 | 1.00 | USP2 (0.44) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL206437 | 1.00 | USP2 (0.44) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL6600866 | 1.00 | USP2 (0.44) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL1828720 | 1.00 | USP2 (0.44) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL204533 | 1.00 | USP2 (0.44) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL5037562 | 0.97 | INMT (0.40) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL1826475 | 0.97 | INMT (0.40) | USP2INMTALDH1A1HPGDMAPT | |
| SCHEMBL25355119 | 0.93 | USP2 (0.39) | USP2INMTALDH1A1 | |
| SCHEMBL17317854 | 0.93 | — | — | |
| SCHEMBL15390690 | 0.93 | USP2 (0.39) | USP2INMTALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069498-B | Tetrahydroisoquinoline derivatives | 细胞动力学股份有限公司 | 2021-08-17 | — | — | CN | disclosed |