SCHEMBL28615344

SCHEMBL28615344

Ic1ccccc1-c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 13/20 0.52
KIF11 P52732 4/20 0.52
ALDH1A1 P00352 1/20 0.46
GPR3 P46089 1/20 0.46
HSD17B10 Q99714 1/20 0.46
BCHE P06276 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733506 0.88 KIF11 (0.63) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL208113 0.88 KIF11 (0.63) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL51674 0.86 KIF11 (0.61) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL30521516 0.86 KIF11 (0.61) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL191654 0.86 KIF11 (0.61) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL3413882 0.84 KIF11 (0.59) KIF11ALDH1A1GPR3HSD17B10BCHE
Lithium SCHEMBL31282245 0.84 KIF11 (0.59) PARP14KIF11ALDH1A1GPR3HSD17B10
SCHEMBL29754924 0.84 KIF11 (0.59) KIF11ALDH1A1GPR3HSD17B10BCHE
Iodide SCHEMBL23782008 0.82 KIF11 (0.57) KIF11ALDH1A1GPR3HSD17B10BCHE
SCHEMBL38651273 0.81 KIF11 (0.55) PARP14KIF11ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122240-B Main and guest doped luminescent material taking iodo-carbazole derivative as main body and preparation and application methods thereof 西北工业大学 2023-08-29 CN disclosed
CN-113122240-A Host-guest doped luminescent material with iodocarbazole derivative as host and preparation and application method thereof 西北工业大学 2021-07-16 CN disclosed