Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 7/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447296 | 0.82 | HDAC3 (0.63) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28627442 | 0.82 | MAPT (0.57) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6904745 | 0.81 | CES1 (0.58) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| Triphenylacetic Acid Methyl Ester SCHEMBL7258414 | 0.77 | KCNN4 (1.00) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19870991 | 0.77 | KCNN4 (0.57) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5635835 | 0.77 | KCNN4 (0.52) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1818707 | 0.75 | PPARA (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2028143 | 0.75 | KCNN4 (0.43) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL616520 | 0.75 | KCNN4 (0.43) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4524605 | 0.74 | HDAC8 (0.63) | KCNN4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214134-B | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113214134-A | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2021-08-06 | — | — | CN | disclosed |