Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447296 | 0.85 | HDAC3 (0.63) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL28615437 | 0.82 | KCNN4 (0.62) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL21378779 | 0.80 | MAPT (0.61) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL6904745 | 0.79 | CES1 (0.58) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL13270940 | 0.78 | MAPT (0.57) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL9035777 | 0.78 | HDAC3 (0.70) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL728471 | 0.78 | KCNN4 (0.67) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL1818707 | 0.78 | PPARA (0.47) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL616520 | 0.78 | KCNN4 (0.43) | MAPTKMT2AKCNN4HDAC3HDAC4 | |
| SCHEMBL9486594 | 0.77 | MAPT (0.62) | MAPTKMT2AKCNN4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214134-B | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113214134-A | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2021-08-06 | — | — | CN | disclosed |