Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28621768 | 0.83 | HDAC6 (0.39) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL28624821 | 0.82 | HDAC6 (0.38) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10745605 | 0.72 | METAP2 (0.51) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10746484 | 0.72 | METAP2 (0.54) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10764046 | 0.69 | METAP2 (0.48) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10748416 | 0.69 | METAP2 (0.48) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10742993 | 0.66 | METAP2 (0.53) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916972 | 0.65 | KAT2A (0.57) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916659 | 0.65 | METAP2 (0.51) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916638 | 0.64 | METAP2 (0.54) | METAP2KDM4EMEN1QSOX1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200978-B | Isothia (selenium) azolone derivative and application thereof in anti-coronavirus drugs | 中国海洋大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-113200978-A | Isothia (selenium) azolone derivative and application thereof in anti-coronavirus drugs | 中国海洋大学 | 2021-08-03 | — | — | CN | disclosed |