Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225517 | 0.88 | TSHR (0.56) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL11316665 | 0.87 | KDM4E (0.57) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL11404248 | 0.85 | KDM4E (0.56) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL8798256 | 0.85 | TSHR (0.56) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL11623299 | 0.84 | TSHR (0.51) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL11623294 | 0.84 | TSHR (0.51) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL25752745 | 0.83 | ALDH1A1 (0.51) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL13048608 | 0.81 | ALDH1A1 (0.52) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL26421295 | 0.81 | TTR (0.49) | TSHRCYP3A4KDM4EGAAALDH1A1 | |
| SCHEMBL15509277 | 0.81 | TSHR (0.60) | TSHRCYP3A4KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |