SCHEMBL2861574

SCHEMBL2861574

O=COC1(c2ccccc2)CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.45
AKR1C1 Q04828 1/20 0.42
HDAC4 P56524 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
CYP2B6 P20813 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
PRCP P42785 1/20 0.40
SLC6A3 Q01959 1/20 0.40
GRIN1 Q05586 1/20 0.40
KCNH2 Q12809 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735252 0.98 DRD3 (0.46) DRD3AKR1C1HDAC4GRIN2DGRIN3B
SCHEMBL5641960 0.94 DRD3 (0.43) DRD3AKR1C1HDAC4OPRM1OPRD1
SCHEMBL348386 0.90 MEN1 (0.39) DRD3AKR1C1OPRM1OPRD1MEN1
SCHEMBL1807152 0.81 SLC6A3 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL694701 0.81 SLC6A4 (0.44) HDAC4SLC6A2SLC6A4SLC6A3
SCHEMBL791817 0.81 SLC6A4 (0.47) AKR1C1GRIN2DGRIN3BCYP2B6SLC6A2
SCHEMBL9329728 0.79 AKR1C1 (0.45) AKR1C1HDAC4GRIN2DGRIN3BCYP2B6
SCHEMBL3815508 0.79 SLC6A2 (0.45) DRD3AKR1C1GRIN2DGRIN3BCYP2B6
SCHEMBL2318965 0.78 HDAC4 (0.42) HDAC4SLC6A2SLC6A4SLC6A3
SCHEMBL4678558 0.78 SMN1; SMN2 (0.39) DRD3OPRM1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119615198-A Electrocatalytic oxidation modification method for indole skeleton-containing compound 浙江工业大学 2025-03-14 CN claimed
CN-108623814-B Copper-based porous coordination polymer hydrogen storage material and preparation method thereof 中国石油化工股份有限公司 2020-10-16 CN claimed
CN-101811986-A Method for producing pentylcyclohexylcyanobenzene JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN claimed
US-20230152693-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-18 US disclosed
CN-108623814-B Copper-based porous coordination polymer hydrogen storage material and preparation method thereof 中国石油化工股份有限公司 2020-10-16 CN disclosed
CN-101827805-B Liquid crystalline compound, liquid crystal composition, and liquid crystal display element CHISSO PETROCHEMICAL CORP 2013-07-10 CN disclosed
CN-102557929-A Chiral bis-naphthyl compounds IND TECH RES INST 2012-07-11 CN disclosed
EP-2253328-A1 Cycloalkyl inhibitors of potassium channel function Bristol-Myers Squibb Company (US) 2010-11-24 EP disclosed
CN-101827805-A Liquid crystalline compound, liquid crystal composition, and liquid crystal display element CHISSO PETROCHEMICAL CORP 2010-09-08 CN disclosed
CN-101811986-A Method for producing pentylcyclohexylcyanobenzene JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN disclosed
CN-101291921-A Spiro [3.3] heptyl-dioxan derivatives and their use in liquid crystal media MERCK PATENT GMBH (DE) 2008-10-22 CN disclosed
CN-1178550-A Electro-optical liquid crystal display MERCK PATENT GMBH (DE) 1998-04-08 CN disclosed
CN-1169743-A Propylene-ethylene copolymer composition and process for producing the same CHISSO CORP (JP) 1998-01-07 CN disclosed
CN-1098725-A Based on porous stretched article of acrylic resin and preparation method thereof NEW JAPAN CHEM CO LTD (JP) 1995-02-15 CN disclosed
EP-0611767-A1 Heterocyclic substituted phenyl-cyclohexan carboxylic acid derivatives as angiotensin II antagonists BAYER AG (DE) 1994-08-24 EP disclosed
CN-1022490-C Liquid crystal mixture BROTSKEY MILITARY TECHNOLOGY A (PL) 1993-10-20 CN disclosed
CN-87101284-A Preparation of liquid crystalline cyclohexylbenzene derivatives and novel nematic mixtures containing them BROTSKEY MILITARY TECHNOLOGY A (PL) 1988-12-14 CN disclosed
US-4336398-A Process for the preparation of basic esters of substituted hydroxycyclohexanecarboxylic acids LABORATORIO GUIDOTTI & C. S.P.A. (IT) 1982-06-22 US disclosed
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US disclosed
US-4010141-A Anti-fouling composition for use in water comprising a polymer and an organo tin compound KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-03-01 US disclosed