Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | REV1 | Q9UBZ9 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597372 | 0.90 | CNR2 (0.46) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597062 | 0.87 | CNR2 (0.44) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597811 | 0.86 | CNR2 (0.48) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL28610577 | 0.86 | KDM4E (0.46) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21603674 | 0.84 | CNR2 (0.47) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597123 | 0.84 | CNR2 (0.48) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL27419058 | 0.84 | LMNA (0.46) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL28607581 | 0.83 | KDM4E (0.60) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597144 | 0.83 | CNR2 (0.46) | CNR2CNR1KDM4EHSD17B10MAPT | |
| SCHEMBL21597173 | 0.83 | CNR2 (0.46) | CNR2CNR1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |