SCHEMBL28615804

SCHEMBL28615804

Cc1cc(OC(N)=O)ccc1I

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
KIF11 P52732 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 1/20 0.38
ACHE P22303 2/20 0.38
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 2/20 0.34
PARP10 Q53GL7 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
PRSS1 P07477 1/20 0.34
ACR P10323 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27282197 0.82 KMT2A (0.57) KMT2AMEN1TDP1L3MBTL1NPC1
SCHEMBL5693949 0.79 KMT2A (0.53) KMT2AMEN1KIF11TDP1L3MBTL1
SCHEMBL25408607 0.79 KMT2A (0.53) KMT2AMEN1TDP1L3MBTL1NPC1
SCHEMBL17242112 0.79 MEN1 (0.53) KMT2AMEN1KIF11TDP1L3MBTL1
SCHEMBL17801666 0.78 KMT2A (0.52) KMT2AMEN1KIF11NPC1ALDH1A1
SCHEMBL28621964 0.78 KMT2A (0.52) KMT2AMEN1KIF11TDP1L3MBTL1
SCHEMBL23753572 0.78 MCL1 (0.56) KMT2AMEN1TDP1L3MBTL1NPC1
SCHEMBL17479464 0.76 KMT2A (0.50) KMT2AMEN1ACHEKDM4EALDH1A1
SCHEMBL2425701 0.76 KMT2A (0.50) KMT2AMEN1TDP1KDM4EALDH1A1
SCHEMBL14543275 0.76 KMT2A (0.53) KMT2AMEN1KIF11TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025189-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2021-07-02 CN disclosed