Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330431 | 0.89 | MET (0.43) | METADORA2AADORA1EGLN1NSD2 | |
| SCHEMBL1163294 | 0.79 | MET (0.44) | METP2RX7 | |
| SCHEMBL20563955 | 0.78 | MET (0.41) | METEGLN1NSD2KDM4ERAB9A | |
| SCHEMBL1329756 | 0.78 | PTGDR2 (0.46) | METKDM4E | |
| SCHEMBL10162620 | 0.77 | MET (0.43) | METADORA2AADORA1SYK | |
| SCHEMBL6520665 | 0.77 | MET (0.43) | METKDM4ERAB9A | |
| SCHEMBL1329076 | 0.77 | MET (0.42) | METKDM4ESYK | |
| SCHEMBL29870122 | 0.77 | MET (0.43) | METKDM4ERAB9A | |
| SCHEMBL28339886 | 0.77 | MET (0.43) | METSYK | |
| SCHEMBL3593816 | 0.77 | MET (0.42) | METKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674073-B | 3, 5-disubstituted-3H-imidazo [4,5-B ] pyridine compounds as modulators of protein kinases | 印蔻真治疗公司 | 2021-09-10 | — | — | CN | disclosed |