Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247137 | 0.80 | HTR6 (0.72) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL29459650 | 0.80 | HTR6 (0.72) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL29509279 | 0.78 | HTR6 (0.73) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL31021 | 0.78 | HTR6 (0.73) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL20531428 | 0.76 | KMT2A (0.61) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL11974983 | 0.76 | KMT2A (0.61) | KMT2AHTR6LMNAL3MBTL1HDAC1 | |
| SCHEMBL257765 | 0.76 | HTR6 (0.70) | KMT2AHTR6PLAULMNAHDAC1 | |
| SCHEMBL6087734 | 0.76 | HTR6 (0.70) | KMT2AHTR6PLAUL3MBTL1HDAC1 | |
| SCHEMBL6085799 | 0.76 | HTR6 (0.70) | KMT2AHTR6PLAUHDAC1HDAC2 | |
| SCHEMBL21335591 | 0.76 | HTR6 (0.70) | KMT2AHTR6PLAUHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530335-B | Indole compound and preparation method and application thereof | 华南农业大学 | 2021-08-31 | — | — | CN | disclosed |