Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353542 | 0.85 | — | — | |
| SCHEMBL216307 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL27479122 | 0.83 | CYP3A4 (0.94) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| SCHEMBL28859723 | 0.83 | CYP3A4 (0.94) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| Sulfuric Acid SCHEMBL21853936 | 0.77 | TSHR (0.73) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| Alcohol SCHEMBL28369215 | 0.77 | ERN1 (0.52) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| Alcohol SCHEMBL28513353 | 0.76 | TDP1 (0.70) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| SCHEMBL29758099 | 0.74 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| SCHEMBL358331 | 0.74 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 | |
| Alcohol SCHEMBL15520191 | 0.74 | ALDH1A1 (0.47) | CYP3A4SMN1; SMN2TSHRALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113322677-B | Reinforced heat-resistant optical cable filler and preparation method thereof | 杭州富通通信技术股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-113322677-A | Reinforced heat-resistant optical cable filler and preparation method thereof | 杭州富通通信技术股份有限公司 | 2021-08-31 | — | — | CN | disclosed |