Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 11/20 | 0.37 |
| ▸ | CDK2 | P24941 | 9/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925193 | 0.79 | PRKCI (0.42) | PRKCIMAPTCDC7CDK2BRPF1 | |
| SCHEMBL31413331 | 0.79 | PRKCI (0.42) | PRKCIMAPTCDC7CDK2BRPF1 | |
| SCHEMBL15712770 | 0.77 | SMN1; SMN2 (0.55) | PRKCIMAPTCDC7CDK2SMN1; SMN2 | |
| SCHEMBL28942939 | 0.72 | CDC7 (0.51) | PRKCIMAPTCDC7CDK2ROCK1 | |
| SCHEMBL31413327 | 0.71 | PRKCI (0.38) | PRKCIMAPTCDC7CDK2BRPF1 | |
| SCHEMBL21925198 | 0.71 | PRKCI (0.38) | PRKCIMAPTCDC7CDK2BRPF1 | |
| SCHEMBL31413335 | 0.71 | MAPT (0.54) | MAPTROCK1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL21925197 | 0.71 | MAPT (0.54) | MAPTROCK1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL27939752 | 0.71 | CA12 (0.44) | MAPTCDC7CDK2MAP3K14SMN1; SMN2 | |
| SCHEMBL29755944 | 0.71 | PRKCI (0.57) | PRKCIMAPTBRPF1ROCK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113286581-A | Intraocular or oral administration of pharmaceutical compositions for the treatment of retinal diseases | 扶桑药品工业株式会社 | 2021-08-20 | — | — | CN | disclosed |