Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 2/20 | 0.40 |
| ▸ | SDC2 | P34741 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099526 | 0.79 | SDCBP (0.47) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL19475669 | 0.72 | HSD17B3 (0.39) | SDCBPSDC2KDM4EHSD17B3PARP1 | |
| SCHEMBL2144912 | 0.72 | SDCBP (0.48) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL1500134 | 0.72 | SDCBP (0.42) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL30336648 | 0.72 | SDCBP (0.42) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL16098139 | 0.72 | SDCBP (0.44) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL18065186 | 0.69 | SDCBP (0.41) | SDCBPSDC2PRMT5WDR77SRD5A1 | |
| SCHEMBL3051492 | 0.68 | NPC1 (0.65) | SDCBPSDC2PRMT5WDR77MEN1 | |
| SCHEMBL1500111 | 0.68 | HDAC1 (0.49) | PRMT5WDR77KDM4EALOX15TSHR | |
| SCHEMBL290250 | 0.67 | BRD4 (0.56) | SDCBPSDC2PRMT5WDR77SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849034-B | EGFR inhibitors and methods of use thereof | 达纳－法伯癌症研究所公司 | 2021-09-03 | — | — | CN | disclosed |