Sugi Predict

Sugi Predict / Targets / SDCBP

SDCBP

Syntenin-1 · O00560 · SDCBP on Sugi Atlas →

4,036 patent compounds predicted against SDCBP, 1,539 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2179112 SCHEMBL2179112 0.52 9/20
SCHEMBL2181199 SCHEMBL2181199 0.76 8/20
SCHEMBL2177896 SCHEMBL2177896 0.65 8/20
SCHEMBL2177628 SCHEMBL2177628 0.61 8/20
SCHEMBL1500322 SCHEMBL1500322 0.59 8/20
SCHEMBL2180951 SCHEMBL2180951 0.56 8/20
SCHEMBL2180875 SCHEMBL2180875 0.51 8/20
SCHEMBL7063991 SCHEMBL7063991 0.49 8/20
SCHEMBL7063999 SCHEMBL7063999 0.49 8/20
SCHEMBL2181074 SCHEMBL2181074 0.63 7/20
SCHEMBL7415929 SCHEMBL7415929 0.60 7/20
SCHEMBL7415930 SCHEMBL7415930 0.60 7/20
SCHEMBL1500260 SCHEMBL1500260 0.58 7/20
SCHEMBL1500172 SCHEMBL1500172 0.55 7/20
SCHEMBL7064833 SCHEMBL7064833 0.47 7/20
SCHEMBL7064840 SCHEMBL7064840 0.47 7/20
SCHEMBL1500196 SCHEMBL1500196 0.57 6/20
SCHEMBL2176682 SCHEMBL2176682 0.56 6/20
SCHEMBL2176688 SCHEMBL2176688 0.56 6/20
SCHEMBL8141859 SCHEMBL8141859 0.55 6/20

Clinical trials — most relevant to SDCBP by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers PHASE4COMPLETED
The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa PHASE2/PHASE3UNKNOWN
The Synapse Project PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma PHASE2RECRUITING
NG2 and DLL3 CAR-T Cells Targeting Melanoma PHASE1/PHASE2RECRUITING
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors PHASE1COMPLETED
Syndecan-1 a Surrogate Marker for IBD nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Myoglobin Removal With CytoSorb in Rhabdomyolysis nanCOMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Clinically Actionable Tumor-Associated Antigens in Prostate Cancer nanACTIVE_NOT_RECRUITING
Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy nanACTIVE_NOT_RECRUITING
When the Kidney Reacts to Nutritional Changes nanCOMPLETED
Seminal Level of Clusterin Before Testicular Sperm Extraction nanUNKNOWN
Detection of Circulating Biomarkers of Immunogenic Cell Death nanCOMPLETED
Study of GPC-3 CAR-T Cells in Treating With Hepatocellular Carcinoma nanRECRUITING
The Activation of Hippo Pathway in Nasal Polyps nanUNKNOWN
Genetic Identification (ID) of Segmental Dysplastic Nevi nanWITHDRAWN
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma nanCOMPLETED
Combined Aerobic Exercise and Cognitive Training in Seniors at Increased Risk for Alzheimer's Disease nanNOT_YET_RECRUITING
Arterial Composition and Cardiovascular Outcome in DIabeteS nanUNKNOWN
Biomarkers of Lichen Sclerosus nanUNKNOWN
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster. nanRECRUITING
A Family Study of Copy Number Variations in Patients With Autism Spectrum Disorder nanCOMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury nanCOMPLETED
Prognostic Markers of Gynecologic Cancers nanCOMPLETED
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SDCBP binder may also engage these)

ProteinNameSimilarity
Q9JI92 — 0.999 Q9JI92 →
O08992 — 0.999 O08992 →
Q4KLN0 — 0.978 Q4KLN0 →
Q99JZ0 — 0.975 Q99JZ0 →
Q5PYH7 — 0.972 Q5PYH7 →
MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 0.972 landscape →
Q9H190 — 0.968 Q9H190 →
Q8BPM2 — 0.968 Q8BPM2 →
Q9WVQ1 — 0.967 Q9WVQ1 →
Q5PYH6 — 0.966 Q5PYH6 →
Q9JLB0 — 0.965 Q9JLB0 →
O88382 — 0.965 O88382 →
Q8BWW9 — 0.965 Q8BWW9 →
Q92796 — 0.965 Q92796 →
P39447 — 0.964 P39447 →
Q28C55 — 0.964 Q28C55 →
A7MBL8 — 0.964 A7MBL8 →
Q95168 — 0.964 Q95168 →
Q6P0D7 — 0.963 Q6P0D7 →
Q8QFR2 — 0.963 Q8QFR2 →
PKN2 Serine/threonine-protein kinase N2 0.963 landscape →
Q6EDY6 — 0.961 Q6EDY6 →
Q86UL8 — 0.961 Q86UL8 →
MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 0.961 landscape →
P70175 — 0.960 P70175 →
Q5E9E1 — 0.960 Q5E9E1 →
Q9UDY2 — 0.960 Q9UDY2 →
Q924I2 — 0.960 Q924I2 →
A8KBF6 — 0.960 A8KBF6 →
A8E0R9 — 0.960 A8E0R9 →