SCHEMBL28617049

SCHEMBL28617049

COc1cc(/C=C/C(=O)NC2(C(=O)O)CCCC2)ccc1OCc1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.52
KDM4E B2RXH2 2/20 0.52
CA2 P00918 1/20 0.49
CA5A P35218 1/20 0.49
CA9 Q16790 1/20 0.49
APP P05067 7/20 0.48
BCHE P06276 6/20 0.47
ACHE P22303 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
STAT1 P42224 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766339 1.00 ALDH1A1 (0.54) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28617053 1.00 ALDH1A1 (0.54) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28617056 0.99 ALDH1A1 (0.53) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28617059 0.99 ALDH1A1 (0.53) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL29766340 0.99 ALDH1A1 (0.53) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28632817 0.90 ALDH1A1 (0.49) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28632819 0.90 ALDH1A1 (0.49) ALDH1A1HPGDHTTRECQLKDM4E
SCHEMBL28634985 0.90 ALDH1A1 (0.53) ALDH1A1HPGDHTTKDM4ECA2
SCHEMBL28634987 0.90 ALDH1A1 (0.53) ALDH1A1HPGDHTTKDM4ECA2
SCHEMBL28922684 0.89 HPGD (0.68) ALDH1A1HPGDHTTKDM4EAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113233993-B Ferulic acid amide derivative and synthetic method thereof 贵州大学 2022-07-01 CN disclosed
CN-113233993-A Ferulic acid amide derivative and synthetic method thereof 贵州大学 2021-08-10 CN disclosed